Wednesday, September 14, 2022

Based Pairs


A 'factory reset' for the brain may cure anxiety, drinking behavior, study suggests: Gene editing reverses brain genetic reprogramming caused by adolescent binge drinking 
May 2022, ScienceDaily

CRISPR Cocktail:
"Early binge drinking can have long-lasting and significant effects on the brain and the results of this study offer evidence that gene editing is a potential antidote to these effects, offering a kind of factory reset for the brain, if you will," 

via University of Illinois Chicago: Targeted epigenomic editing ameliorates adult anxiety and excessive drinking after adolescent alcohol exposure. John Peyton W. Bohnsack, et al. Science Advances, 2022; 8 (18) DOI: 10.1126/sciadv.abn2748


Researchers find CRISPR-Cas9 gene editing approach can alter the social behavior of animals
May 2022, phys.org

The old switcheroo:
"We were really surprised at the results," Albers said. "We anticipated that if we eliminated vasopressin activity, we would reduce both aggression and social communication. But the opposite happened."

via Georgia State University: Jack H. Taylor et al, CRISPR-Cas9 editing of the arginine–vasopressin V1a receptor produces paradoxical changes in social behavior in Syrian hamsters, Proceedings of the National Academy of Sciences (2022). DOI: 10.1073/pnas.2121037119


Image credit: No credits, a computer made it! But I call it "Lobotomy in Alaska", from Lexica's library.


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