Showing posts with label optogenetics. Show all posts
Showing posts with label optogenetics. Show all posts

Wednesday, January 11, 2023

Brain Lasers


Short term memory problems can be improved with laser therapy, according to new study
Dec 2022, phys.org

Non-invasive:
Could improve short term, or working memory in people by up to 25%. The treatment, called transcranial photobiomodulation (tPBM), is applied to an area of the brain known as the right prefrontal cortex. 

via University of Birmingham and Beijing Normal University in China: Chenguang Zhao et al, Transcranial photobiomodulation enhances visual working memory capacity in humans, Science Advances (2022). DOI: 10.1126/sciadv.abq3211.


System that uses light stimulation to modulate brain waves
Oct 2022, phys.org

Small implant containing LEDs placed inside the brain to deliver light directly. Opsin proteins within brain cells were altered using a gene therapy to make them sensitive to light.

The technique of closed-loop optical neurostimulation "allowed us to boost or suppress brain waves." 

Successfully suppressed abnormal brain waves that resembled epileptic seizures.

via Newcastle University: B. Zaaimi et al, Closed-loop optogenetic control of the dynamics of neural activity in non-human primates, Nature Biomedical Engineering (2022). DOI: 10.1038/s41551-022-00945-8


New flexible, steerable device placed in live brains by minimally invasive robot
Oct 2022, phys.org

Only minimally invasive:
Robotically delivered brain surgery, using bioinspired steerable catheter, inspired by organs used by parasitic wasps to stealthily lay eggs in tree bark, and connected to to a robotic platform that combines human input and machine learning to carefully steer the catheter.

via Imperial College London: Riccardo Secoli et al, Modular robotic platform for precision neurosurgery with a bio-inspired needle: System overview and first in-vivo deployment, PLOS ONE (2022). DOI: 10.1371/journal.pone.0275686


Saturday, December 9, 2017

Think About This

Dr. Frankenstein Light Switch, turn it up.

Carefully crafted light pulses control neuron activity
Nov 2017, phys.org

Specially tailored, ultrafast pulses of light can trigger neurons to fire and could one day help patients with light-sensitive circadian or mood problems, according to a new study in mice at the University of Illinois.

The study used optogenetic mouse neurons - that is, cells that had a gene added to make them respond to light.

"What we're doing for the very first time is using light and coherent control to regulate biological function.