Showing posts with label bioengineering. Show all posts
Showing posts with label bioengineering. Show all posts

Wednesday, September 18, 2024

Buildings, Bodies and Biocompatibility


How are ancient Roman and Mayan buildings still standing? Scientists are unlocking their secrets
Oct 2023, phys.org

There's 2,000-year-old concrete still looking like the day it was poured. And there's also the front steps of my friend's apartment that's been crumbling since the day it got repaired. 

What's the difference? 

Some of these ancient builders might have just gotten lucky, said Cecilia Pesce, a materials scientist at the University of Sheffield in England. They'd toss just about anything into their mixes, as long as it was cheap and available—and the ones that didn't work out have long since collapsed.

"They would put all sorts of things in construction," Pesce said. "And now, we only have the buildings that survived. So it's like a natural selection process."

But alas, there does seem to be a pattern:
In a study published earlier this year, Admir Masic, a civil and environmental engineer at the Massachusetts Institute of Technology, proposed that this power comes from chunks of lime that are studded throughout the Roman material instead of being mixed in evenly. Researchers used to think these chunks were a sign that the Romans weren't mixing up their materials well enough.

Instead, after analyzing concrete samples from Privernum -- an ancient city outside of Rome -- the scientists found that the chunks could fuel the material's "self-healing" abilities. When cracks form, water is able to seep into the concrete, Masic explained. That water activates the leftover pockets of lime, sparking up new chemical reactions that can fill in the damaged sections.
via MIT



Catalysis breakthrough yields self-cleaning wall paint that breaks down air pollutants when exposed to sunlight
Mar 2024, phys.org

The UV radiation creates free charge carriers in the particles, which induce decomposition of the trapped pollutants from air into small parts and their release. In this way, the pollutants are rendered harmless, but do not remain permanently attached to the wall paint. The wall color remains stable in the long term. The new particles work with ordinary sunlight by adding certain additional atoms to the titanium oxide nanoparticles, such as phosphorus, nitrogen, and carbon.

via Vienna University of Technology and Università Politecnica delle Marche: Qaisar Maqbool et al, Highly Stable Self-Cleaning Paints Based on Waste-Valorized PNC-Doped TiO2 Nanoparticles, ACS Catalysis (2024). DOI: 10.1021/acscatal.3c06203


Veins of bacteria could form a self-healing system for concrete infrastructure
Dec 2023, phys.org

Fiber reinforcement has been around since the first masons mixed horsehair into their mud. 

BioFiber - polymer fiber encased in a bacteria-laden hydrogel and a protective, damage-responsive shell. The team reports that a grid of BioFibers embedded within a concrete structure can improve its durability, prevent cracks from growing, and enable self-healing.

It uses biomineralizing bacteria, aka microbial-induced calcium carbonate precipitation.

via Drexel University: Mohammad Houshmand Khaneghahi et al, Development of a nature-inspired polymeric fiber (BioFiber) for advanced delivery of self-healing agents into concrete, Construction and Building Materials (2023). DOI: 10.1016/j.conbuildmat.2023.133765


New AI tool discovers realistic 'metamaterials' with unusual properties
Feb 2024, phys.org

They call it "inverse design"

"Tell us what you want to have as properties and we engineer an appropriate material with those properties. What you will then get is not really a material but something in-between a structure and a material, a metamaterial" 

via Delft University of Technology Department of Biomechanical Engineering: Helda Pahlavani et al, Deep Learning for Size‐Agnostic Inverse Design of Random‐Network 3D Printed Mechanical Metamaterials, Advanced Materials (2023). DOI: 10.1002/adma.202303481

AI Art - Regenerative Plant Researcher 2 - 2024

New all-liquid iron flow battery for grid energy storage
Mar 2024, phys.org

A commonplace chemical used in water treatment facilities has been repurposed for large-scale energy storage in a new battery design for an iron-based flow battery.

It stores energy in a unique liquid chemical formula that combines charged iron with a neutral-pH phosphate-based liquid electrolyte, or energy carrier. 

The chemical, nitrogenous triphosphonate, nitrilotri-methylphosphonic acid or NTMPA, is commercially available in industrial quantities because it is typically used to inhibit corrosion in water treatment plants.

via Pacific Northwest National Laboratory: Phosphonate-based Iron Complex for a Cost-Effective and Long Cycling Aqueous Iron Redox Flow Battery, Nature Communications (2024). DOI: 10.1038/s41467-024-45862-3


Biodegradable aerogel: Airy cellulose from a 3D printer
Apr 2024, phys.org

Using the most common biopolymer on Earth (cellulose), they created a cellulose-based, 3D-printable aerogel, made of nanofibers for viscosity and nanocrystals so that it flows more easily during extrusion. To turn the ink into an aerogel after printing, the researchers replace the pore solvent water first with ethanol and then with air, all while maintaining shape fidelity.

It's an extremely effective heat insulator, and it's biocompatible with living tissues and cells.

It also can be rehydrated and re-dried several times after the initial drying process without losing its shape or porous structure, so it can be stored and transported in dry form and only be soaked in water shortly before use.

via Swiss Federal Laboratories for Materials Science and Technology: Deeptanshu Sivaraman et al, Additive Manufacturing of Nanocellulose Aerogels with Structure‐Oriented Thermal, Mechanical, and Biological Properties, Advanced Science (2024). DOI: 10.1002/advs.202307921


Sunrise to sunset, a new window coating blocks heat, not view
Apr 2024, phys.org

Some window coatings work for a 90-degree angle. Yet at the hottest time of day, the sun's rays enter at oblique angles.

They fabricated a transparent window coating by stacking ultra-thin layers of silica, alumina and titanium oxide on a glass base, with a micrometer-thick silicon polymer added to enhance cooling power. To shuffle the layers into an optimal configuration the team used quantum computing, or more specifically, quantum annealing, and validated their results experimentally.

(Note: We're now using quantum computers to validate experiments, and this is kind of the real story here.)

via University of Notre Dame: Seongmin Kim et al, Wide-angle spectral filter for energy-saving windows designed by quantum annealing-enhanced active learning, Cell Reports Physical Science (2024). DOI: 10.1016/j.xcrp.2024.101847

AI Art - Regenerative Plant Researcher 3 - 2024

How buildings influence the microbiome and human health
Apr 2024, phys.org

Modern buildings have a significant influence on human microbial colonization, depending on their nature and degree of shielding from the environment, and that this aspect should be taken into account in future architecture in terms of healthy and microbiome-friendly building conditions.

Buildings interrupt contact with microorganisms from the environment.

Future architecture should restore permeability for microorganisms.

Buildings themselves must be viewed as complex organic systems in the sense of countless interdependent microbial communities, which also have an impact on the human metaorganism.

Taken together, this has negative consequences, for example by creating new niches for disease hosts and vectors in buildings, concentrating waste and toxic substances or reducing ventilation and the entry of sunlight.

According to the researchers, one aim could therefore be to plan and construct the built environment in future in such a way that the focus is not on complete isolation from the natural, microbial environment. On the contrary: buildings can be opened up to nature again and made more nature-friendly.

This can be achieved, for example, by using less toxic building materials and creating an overall greater structural permeability to external, particularly microbial, influences.

via Kiel University Collaborative Research Center 1182 Origin and Function of Metaorganisms and the Canadian Institute for Advanced Research in Toronto, Columbia University, University of Oregon, California Institute of Technology: Thomas C. G. Bosch et al, The potential importance of the built-environment microbiome and its impact on human health, Proceedings of the National Academy of Sciences (2024). DOI: 10.1073/pnas.2313971121


Intelligent liquid: Researchers develop metafluid with programmable response
Apr 2024, phys.org

This came out in April 2024 - How the hell was this not in any other headlines? This is literally the T-1000 

They developed a programmable metafluid with tunable springiness, optical properties, viscosity and can transition between a Newtonian and non-Newtonian fluid.

It's a suspension of small, elastomer spheres between 50 to 500 microns that buckle under pressure,  changing the characteristics of the fluid.

A new class of fluid.

With this metafluid, no sensing is needed. The liquid itself responds to different pressures, changing its compliance to adjust the force of the gripper to be able to pick up a heavy bottle, a delicate egg and a small blueberry, with no additional programming.

Also this line:

"We show that we can use this fluid to endow intelligence into a simple robot"
(Because that is exactly what we all want right now.)

via Harvard John A. Paulson School of Engineering and Applied Sciences:  Katia Bertoldi, Shell buckling for programmable metafluids, Nature (2024). DOI: 10.1038/s41586-024-07163-z.

Thursday, August 1, 2024

Manplants, Transplants and Anthropologizing of the Biosphere


Researchers show that introduced tardigrade proteins can slow metabolism in human cells
Mar 2024, phys.org

This work examines the mechanisms used by tardigrades to enter and exit from suspended animation when faced by environmental stress, and provides additional evidence that tardigrade proteins eventually could be used to make life-saving treatments available to people where refrigeration is not possible—and enhance storage of cell-based therapies, such as stem cells.

"Amazingly, when we introduce these proteins into human cells, they gel and slow down metabolism, just like in tardigrades"

The whole process is reversible. "When the stress is relieved, the tardigrade gels dissolve, and the human cells return to their normal metabolism"

via University of Wyoming Department of Molecular Biology, University of Bristol, Washington University in St. Louis, University of California-Merced, University of Bologna, University of Amsterdam: S. Sanchez‐Martinez et al, Labile assembly of a tardigrade protein induces biostasis, Protein Science (2024). DOI: 10.1002/pro.4941



By growing animal cells in rice grains, scientists dish up hybrid food
Feb 2024, phys.org

"hybrid meat rice" 

Rice grains are porous and have organized structures, providing a solid scaffold to house animal-derived cells in the nooks and crannies. Certain molecules found in rice can also nourish and promote the growth of these cells, making rice an ideal platform.

The team first coated rice with fish gelatin, a safe and edible ingredient that helps cells latch onto the rice better. Cow muscle and fat stem cells were then seeded into the rice and left to culture in the petri dish for nine to 11 days. The harvested final product is a cell-cultured beef rice with main ingredients that meet food safety requirements and have a low risk of triggering food allergies.

via Yonsei University in Korea: Rice grains integrated with animal cells: A Shortcut to a Sustainable Food System, Matter (2024). DOI: 10.1016/j.matt.2024.01.015.


Montana man used animal tissue and testicles to breed 'giant' sheep for sale to hunting preserves
Mar 2024, AP News

Court documents describe a yearslong conspiracy, beginning in 2013, in which Schubarth and at least five other people sought to create “giant sheep hybrids” by cross-breeding different species. Their goal was to garner high prices from hunting preserves where people shoot captive trophy game animals for a fee.

Using biological tissue obtained from a hunter who killed a wild sheep in Kyrgyzstan belonging to the world’s largest species of the animals — Marco Polo argali sheep — Schubarth procured cloned embryos of the animal from a lab, according to court documents.

The embryos were later implanted in a ewe, resulting in a pure Marco Polo argali sheep that Schubert named “Montana Mountain King,” the documents show. Semen from Montana Mountain King was used to artificially impregnate other ewes to create a larger and more valuable species of sheep, including one offspring that he reached an agreement to sell to two people in Texas for $10,000, according to the documents.

In 2019, Schubarth paid $400 to a hunting guide for testicles from a trophy-sized Rocky Mountain bighorn sheep killed in Montana. Schubarth extracted semen from bighorn sheep testicles and used it to breed large bighorn sheep and sheep crossbred with the argali species, the documents show.

Friday, July 10, 2020

Thank You Japan


Blowing bubbles - Soapy spheres pop pollen on fruit trees
June 2020, BBC News

Just when you think we are doomed by the insectapocalypse and mass bee death in particular, Japanese researchers have succeeded in fertilising pear trees using pollen carried on the thin film of a soap bubble.

Post Script
Once in a while I run an image search for something I think is totally random and will return equally random results, like "bumblebee porn". Well I'm here to remind you that anything-porn is not random. You can type [anything] porn and get a relevant result.

In this case, bumblebee is a transformer (although I don't recall this character from the originals circa early 1980's), and maybe he got a movie made recently, so he takes over the top results. And yes he's a robot, and yes robophilia is a thing. And on that note, I must recall the artist of sexy robot fame, Hajime Sorayama (also Japanese, thanks again).

-image source: David Prutchi, Ultraviolet Vision