Thursday, March 31, 2022

GPS My Biodata


Global study of 6 cities' microbes finds each has a signature microbial fingerprint
May 2021, phys.org

The largest-ever global metagenomic study of urban microbiomes"

"If you gave me your shoe, I could tell you with about 90% accuracy the city in the world from which you came."
-Christopher Mason, professor at Weill Cornell Medicine, director of the WorldQuant Initiative for Quantitative Prediction, and senior author 

The group oversees projects such as Global City Sampling Day (gCSD), held every year on June 21, and has done wide-ranging studies including a comprehensive microbial analysis of Rio de Janeiro's city surfaces and its mosquitoes before, during, and after the 2016 Summer Olympics. 

via an international consortium of 69 authors: Cell, Danko et al.: "A global metagenomic map of urban microbiomes and antimicrobial resistance" DOI: 10.1016/j.cell.2021.05.002

Post Script:
Scaling laws in enzymes may help predict life 'as we don't know it'
Mar 2022, phys.org

"Universal laws that should apply to any biochemical system"

Using the Integrated Microbial Genomes and Microbiomes database, the team investigated the enzymes—the functional drivers of biochemistry—found in bacteria, archaea, and eukarya to reveal a new kind of biochemical universality.

The team compared how the abundance of enzymes in functional categories changed in relation to the overall abundance of enzymes in an organism. They discovered various scaling laws between the number of enzymes in different enzyme classes and the size of an organism's genome. They also found that these laws don't depend on the particular enzymes in those classes. [It's universal.]

via Santa Fe Institute and NASA: Dylan C. Gagler et al, Scaling laws in enzyme function reveal a new kind of biochemical universality, Proceedings of the National Academy of Sciences (2022). DOI: 10.1073/pnas.2106655119


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