Sunday, January 5, 2025

Nature's Palette Prompts Advances in Color Tech


Ecocidal maniacs consider alternatives to destroying the planet with glitter:

Bacterial glitter - New findings open up possibilities for sustainable color technologies
Jul 2024, phys.org

Scientists sequenced the DNA of 87 structurally colored bacteria and 30 colorless strains and identified genes that are responsible for these fascinating colonies. 

"We discovered that the genes responsible for structural color are mainly found in oceans, freshwater, and special habitats such as intertidal zones and deep-sea areas. In contrast, microbes in host-associated habitats such as the human microbiome displayed very limited structural color,"

Surprisingly, these genes are also found in bacteria that live in deep oceans without sunlight. This could imply that the colors could reflect deeper processes of cell organization with important functions, such as protecting the bacteria from viruses, or efficiently colonizing floating food particles.

via Friedrich Schiller University of Jena, Max Planck Institute of Colloids and Interfaces, Leibniz Institute DSMZ-German Collection of Microorganisms and Cell Cultures, Utrecht University, University of Cambridge, and the Netherlands Institute for Sea Research: Colin J. Ingham et al, Structural color in the bacterial domain: The ecogenomics of a 2-dimensional optical phenotype, Proceedings of the National Academy of Sciences (2024). DOI: 10.1073/pnas.2309757121

Related image credit: Wing scales of a butterfly Papilio ulysses on a medical syringe needle - Daniel Knop Nikon Small World 12th Place - 2024 [link]


Study reveals why orange netting packaging makes oranges look more appealing
Aug 2024, phys.org

The "confetti illusion" - Food growers learned a long time ago that if they packed oranges in orange netting, the oranges inside look more orange, which the mind interprets as a more luscious ripe fruit. The same thing is true for yellow netting for lemons and green netting for limes. 

This research shows that the change in fruit color is not due to the way light reflects off the netting but that sensory stimuli are made of partial information and assembled into images only after the brain has knitted together input from several sources. 

via Giessen University: Karl R. Gegenfurtner, Perceptual ripening of oranges, i-Perception (2024). DOI: 10.1177/20416695241258748


Synthetic molecular switch enables 'painting' with natural light
Oct 2024, phys.org

A synthetic molecular switch made up of the organic molecule triptycene and a class of compounds called hydrazones can trigger shape changes in liquid crystals that allow them to reflect different colors. 

When chiral triptycene interacts with a liquid crystal molecule, it rearranges other liquid crystal molecules in twisted, DNA-like helices, which then reflect ambient light at different wavelengths based on their pitch, or how far apart the coils in their helical structure are spaced.

via Dartmouth and Southern Methodist University: Indu Bala et al, Multi-stage and multi-colour liquid crystal reflections using a chiral triptycene photoswitchable dopant, Nature Chemistry (2024). DOI: 10.1038/s41557-024-01648-0

Saturday, January 4, 2025

Measuring Things for Old Time's Sake


Starting with a stretch, this first one requires some concentration. We're talking about macro time vs micro time, and one where the time is measured by genetic changes. It's a new way to measure evolutionary time. Also it's scalar, which means fractals:

New research shows microevolution can be used to predict how evolution works on much longer timescales
May 2024, phys.org

By compiling and analyzing datasets from existing species and from fossils, researchers showed the evolvability responsible for microevolution (the evolution of a species over a few generations) of many different traits predicts the amount of change observed between populations and species separated by up to one million years (macroevolution).

"Darwin suggested that species gradually evolve, but what we found is that even though populations rapidly evolve over the short term, this (short-term) evolution doesn't accumulate over time. However, how divergent populations and species are, on average, over long periods of time still depends on their ability to evolve on the short term." 

via Norwegian University of Science and Technology Department of Biology: Agnes Holstad et al, Evolvability predicts macroevolution under fluctuating selection, Science (2024). DOI: 10.1126/science.adi8722

Further reading, from above: Traits with higher evolvability change rapidly because they are able to respond to environmental changes more quickly.

Highly evolvable traits can rapidly respond to these fluctuations in selection and will fluctuate over time with high amplitude. Traits with little evolvability will also fluctuate but more slowly and thus with lower amplitude.

"Populations or species that are geographically distant from each other are exposed to environments whose fluctuations are not synchronized. Consequently, these populations will have different trait values, and the size of this difference will depend on the amplitude of the trait's fluctuation, and therefore on the evolvability of the trait."

Note: "Evolvability" depends on the amount of heritable (genetic) variation in a species (which sounds like heterozygosity?).



Researchers more precisely calculate how much faster time passes on the moon
Jul 2024, phys.org

The team found that time on the moon ticks by at 0.0000575 seconds faster per day (57.50 µs/d) than it does on Earth. Based on that number, other calculations can be made - if a person were to live on the moon for 274 years, for example, they would be 5.76 seconds older than they would be had they lived on Earth all that time.

It doesn't seem like a big deal until you try to do something like dock with a space station.

via NASA's Jet Propulsion Laboratory at the California Institute of Technology: Slava G. Turyshev et al, Time transformation between the solar system barycenter and the surfaces of the Earth and Moon, arXiv (2024). DOI: 10.48550/arxiv.2406.16147


Why timekeeping is now on the verge of a giant leap forward in accuracy
Nov 2024, phys.org

Atomic clocks are about to be replaced by nuclear clocks that can use the Thorium atom instead of the Cesium or Strontium atom, because it has a faster electron transition, so with it we can measure time to the nineteenth decimal place, possibly redefining the second by 2030.

Some background:
  • Water clocks appeared around 2,000BC and measure time by regulating the flow of water into or out of a vessel.
  • The mechanical clock was established in the late 13th century.
  • Until 1967, a second was defined as 1/86,400 of a day.
  • The International System of Units then changed things: "The second… is defined by taking the… transition frequency of the cesium-133 atom, to be 9192631770 when expressed in the unit Hz, which is equal to s⁻¹."

Bonus: 
Scientists successfully create a time crystal made of giant atoms
Jul 2024, phys.org

via Vienna University of Technology Institute of Theoretical Physics and Tsinghua University: Xiaoling Wu et al, Dissipative time crystal in a strongly interacting Rydberg gas, Nature Physics (2024). DOI: 10.1038/s41567-024-02542-9.

Friday, January 3, 2025

Entropy Engineering and Social Syncopation


Singing researchers find cross-cultural patterns in music and language
May 2024, phys.org

An international team of researchers recorded themselves performing traditional music and speaking in their native language. In all 50+ languages, the rhythms of songs and instrumental melodies were slower than those of speech, while the pitches were higher and more stable.

Speculating on underlying reasons for the cross-cultural similarities, Savage suggests songs are more predictably regular than speech because they are used to facilitate synchronization and social bonding.

"Slow, regular, predictable melodies make it easier for us to sing together in large groups," he says. "We're trying to shed light on the cultural and biological evolution of two systems that make us human: music and language."

via Max Planck Institute for Psycholinguistics in Nijmegen: Yuto Ozaki et al, Globally, songs and instrumental melodies are slower, higher, and use more stable pitches than speech: A Registered Report, Science Advances (2024). DOI: 10.1126/sciadv.adm9797. 



Neuroplasticity study shows how singing rehabilitates speech production in post-stroke aphasia
May 2024, phys.org

According to the findings, singing repairs the structural language network of the brain. The language network processes language and speech in our brain. In patients with aphasia, the network has been damaged.

"For the first time, our findings demonstrate that the rehabilitation of patients with aphasia through singing is based on neuroplasticity changes"

via University of Helsinki: Aleksi J. Sihvonen et al, Structural Neuroplasticity Effects of Singing in Chronic Aphasia, eNeuro (2024). DOI: 10.1523/ENEURO.0408-23.2024


Study shows the power of social connections to predict hit songs
Jun 2024, phys.org

The team analyzed data from last.fm, analyzing 2.7 million users, 10 million songs, and 300 million plays, along with networks of mapping friendships and another capturing influence dynamics (who listens to a song and who follows suit). 

Examining the first 200 plays of a new song, they predicted its chances of becoming a hit.

The researchers improved the precision of predicting hit songs from 14% to 21%.

Existing models often focus on artist fame and listening metrics, but the CSH study highlights the overlooked social aspect - musical homophily, which is the tendency for friends to listen to similar music.

via Complexity Science Hub Vienna: Niklas Reisz et al, Quantifying the impact of homophily and influencer networks on song popularity prediction, Scientific Reports (2024). DOI: 10.1038/s41598-024-58969-w


Understanding the synchronization of physiological states during a live music performance
Jul 2024, phys.org

"Music-induced synchronization of heart rate may be the mechanism underlying the coherent behavior of a large audience in a theater." 

Synchronization of physical and cognitive processes is better within an individual compared to that between different individuals; and heart rate synchronization in response to music depends on the reliable physiological responses of the listener, not on their mood or music preferences.

Note that in the study, to guage mood, they had participants in the study listen to the same piece of music on different days. And to quantify the influence of music preference on heart rate synchronization, he investigated whether a person listening to a piece of music selected by the researcher differed in synchronization response to a piece of music that deeply moves them when played in a randomized order.

Why - "From data on small audiences, for example, the degree of proficiency of performers, commercial success can be predicted in terms of reliability."

via Waseda University: Ryota Nomura, Reliability for music-induced heart rate synchronization, Scientific Reports (2024). DOI: 10.1038/s41598-024-62994-0


Classical music lifts our mood by synchronizing our 'extended amygdala'
Aug 2024, phys.org

The study focused on 13 patients with treatment-resistant depression who already had electrodes implanted in their brains for the purpose of deep-brain stimulation. These implants are placed in a circuit connecting two areas in the forebrain—the bed nucleus of the stria terminalis (BNST) and the nucleus accumbens (NAc). Using these implants, the researchers found that music generates its antidepressant effects by synchronizing the neural oscillations between the auditory cortex, which is responsible for processing of sensory information, and the rewards circuit, which is responsible for processing emotional information.

The patients in the study were assigned to two groups: low music appreciation or high music appreciation. Those in the high music appreciation group demonstrated more significant neural synchronization and better antidepressant effects, while those in the low music appreciation group showed poorer results.  

via Center for Functional Neurosurgery at Shanghai Jiao Tong University: uditory entrainment coordinates cortical-BNST-NAc triple time locking to alleviate the depressive disorder, Cell Reports (2024). DOI: 10.1016/j.celrep.2024.114474. 

Intermission on sonic superpowers:
Singing from memory unlocks a surprisingly common musical superpower
Aug 2024, phys.org

They asked people to sing out any earworms they were experiencing and record them on their phones when prompted at random times throughout the day, and found the majority perfectly matched the pitch of the original songs.

"Surprisingly large portion of the population has a type of automatic, hidden 'perfect pitch' ability."

They think it depends on whether the music was recalled deliberately or as a result of an "earworm", which is why they asked people to record themselves as soon as they hear one in their head. So now they think there may be something unique about musical memories and the ways they are encoded and maintained inside our brains.

via University of California Santa Cruz: Matthew G. Evans et al, Absolute pitch in involuntary musical imagery, Attention, Perception, & Psychophysics (2024). DOI: 10.3758/s13414-024-02936-0


Below are a couple articles recalling the genius of Leonard B. Meyer

Bach, Mozart or jazz: Scientists provide a quantitative measure of variability in music pieces
Nov 2024, phys.org

They even mention Meyer in the write up: "According to Meyer, emotions and meaning in music arise from the interplay of expectations and their fulfillment or (temporary) non-fulfillment."

Sorry I have to copy mostly the whole thing, because this stuff is complicated:

They used time series analysis to infer how similar a tone sequence is to previous sequences (the autocorrelation function of musical pitch sequences).

They analyzed more than 450 jazz improvisations and 99 classical compositions, and found the autocorrelation function of pitches initially decreases slowly with the time difference. This expresses a high similarity and possibility to anticipate musical sequences. 

However, they found that there is a time limit, after which this similarity and predictability ends relatively abruptly. For larger time differences, the autocorrelation function and memory are both negligible.

Of particular interest here are the values of the transition times of the pieces where the more predictable behavior changes into a completely unpredictable and uncorrelated behavior. Depending on the composition or improvisation, the scientists found transition times ranging from a few quarter notes to about 100 quarter notes. Jazz improvisations typically had shorter transition times than many classical compositions, and therefore were usually less predictable.

Differences could also be observed between different composers. For example, the researchers found transition times between five and twelve quarter notes in various compositions by Johann Sebastian Bach, while the transition times in various compositions by Mozart ranged from eight to 22 quarter notes. This implies that the anticipation and expectation of the musical progression tends to last longer in Mozart's compositions than in Bach's compositions, which offer more variability and surprises.

via Max Planck Institute for Dynamics and Self-Organization and the University of Göttingen: Corentin Nelias et al, Stochastic properties of musical time series, Nature Communications (2024). DOI: 10.1038/s41467-024-53155-y


Study explores how brain waves reflect melody predictions while listening to music
Nov 2024, phys.org

We aimed to disentangle the frequency-specific neural dynamics linked to melodic prediction uncertainty (modeled as entropy) and prediction error (modeled as surprisal) for temporal (note onset) and content (note pitch) information."

They recruited 20 participants, half of whom were professional pianists, to listen to 10 piano melodies extracted from the work of Johann Sebastian Bach, each lasting approximately 150 seconds, and while being recorded using electroencephalography (EEG).

"An analysis of the temporal response function (TRF) weights revealed that the temporal predictability of a note (entropy of note onset) may be encoded in the delta- (1–4 Hz) and beta-band (12–30 Hz) brain activity prior to the stimulus, suggesting that these frequency bands associate with temporal predictions."

via Max Planck Institute for Human Cognitive and Brain Sciences: Juan-Daniel Galeano-Otálvaro et al, Neural encoding of melodic expectations in music across EEG frequency bands. European Journal of Neuroscience(2024). DOI: 10.1111/ejn.16581

Further Reading for Meyer-like things:

The Psychological Operator


You probably don't need more reasons to adjust your position relative to the corporate state, but just in case:

“Deny, denounce, delay”: The battle over the risk of ultra-processed foods
May 2024, Ars Technica but Financial Times

When the Brazilian nutritional scientist Carlos Monteiro coined the term “ultra-processed foods” 15 years ago, he established what he calls a “new paradigm” for assessing the impact of diet on health.

Monteiro had noticed that although Brazilian households were spending less on sugar and oil, obesity rates were going up. The paradox could be explained by increased consumption of food that had undergone high levels of processing, such as the addition of preservatives and flavorings or the removal or addition of nutrients.

But health authorities and food companies resisted the link, ...

In 2019, American metabolic scientist Kevin Hall carried out a randomized study comparing people who ate an unprocessed diet with those who followed a UPF diet over two weeks. Hall found that the subjects who ate the ultra-processed diet consumed around 500 more calories per day, more fat and carbohydrates, less protein—and gained weight.

The industry has responded with a ferocious campaign...

The industry has also successfully framed the issue as one of personal choice. ... Manufacturers also argue that the harm caused by their products is a result of a lack of personal willpower or failure to exercise ... 
In summary, all that needs to be said:
Innovations in processing over the 20th century not only made food more affordable and accessible, the industry’s advocates note, but also created beneficial products like sugar-free sweeteners and protein-enriched milk. [aka sugar-free sugar and milk-added milk]

Above image credit: Fruit fly Drosophila brain vasculature - Nikky Corthout and Miranda Dyson for Nikon Small World - 2024 [link]


Vegetarians consume more ultra-processed food than those who regularly eat meat, study finds
Nov 2024, phys.org

This paragraph in itself is just really funny:

Such ultra-processed foods have been found to contain a host of added, sometimes unhealthy, compounds and chemicals to enhance taste, improve texture, help with freshness, or simply make them look more appetizing. Meat, on the other hand, tends to undergo less processing because it looks and tastes good in its natural state.

via Imperial College London, University of São Paulo, and International Agency for Research on Cancer of France: Kiara Chang et al, Plant-based dietary patterns and ultra-processed food consumption: a cross-sectional analysis of the UK Biobank, eClinicalMedicine (2024). DOI: 10.1016/j.eclinm.2024.102931

130,000 brain cells and 50 million connections of a fly - Medical Research Council's Laboratory of Molecular Biology in Cambridge - Oct 2024 [link] It's the most detailed analysis of the brain of an adult animal ever produced.

Opioid giant's tactics to influence doctors revealed in court documents
Jun 2024, phys.org

Opioid giant Mallinckrodt, selling more than Purdue Pharma in the US, was forced by the courts to publish more than 1.3 million internal documents.

  • recruiting physicians to serve as influencers
  • planting articles in scientific journals
  • coordinating conference presentations
  • developing continuing medical education courses

"Creating the term pseudoaddiction and distorting the terms tolerance and dependence were strategies that distracted physicians from noticing their patients were addicted."

Mallinckrodt continues to sell opioids today, with sales up 25% from the year before.

via Department of Philosophy at Queen’s University in Canada, and Institute for Science in Society at Radboud University: How an opioid giant deployed a playbook for moulding doctors' minds, The BMJ (2024). DOI: 10.1136/bmj.q1208


New research reveals that a tobacco company has secretly funded Japanese academics
Jun 2024, phys.org

Every major industry does this:

Philip Morris International (PMI) and its Japanese affiliate, Philip Morris Japan contracted a third-party external research organization to secretly fund a study on smoking cessation conducted by Kyoto University academics (no public record of PMJ's funding or involvement in this study was found), and paid a life sciences consultancy to network with scientists and promote PMI's science and products at academic events (also kept secret both within and outside the company).

PMI has a track record of scientific misconduct and misinformation:

  • The Foundation for a Smoke-Free World (FSFW) claims to be independent, but TCRG research has found that it is solely funded by PMI and published by PMI-favorable research.
  • Journalist investigations and academic reviews of PMI's science have raised serious concerns over the quality and ethical standing of PMI's clinical research.
  • In 2022, a review by TCRG found PMI's clinical trials on its heated tobacco products were at high risk of bias and poor quality.
  • A 2020 TCRG report on PMI detailed the company's "relentless lobbying, PR campaigns and multifaceted approaches to influencing science and public health in order to manage the future direction of tobacco control."

Note: The researchers used the Science for Profit Model—How and why corporations influence science and the use of science in policy and practice, Tess Legg, Jenny Hatchard, Anna B. Gilmore, 2021, PLOS One. https://journals.plos.org/plosone/article?id=10.1371/journal.pone.0253272

Cerebral Organoids - Institute of Industrial Science at University of Tokyo - Apr 2024 [link]

Bonus: 
Clinical trial shows that plant-based cytisinicline can help people quit vaping
May 2024, phys.org

Is this a merry-go-rund or more like musical chairs?

They're a plant-based oral tablet; AKA a pill.

So first you get addicted to cigarettes, then you vape to quit cigarettes, and then you take these pills to quit vaping, and then you ... 

via Massachusetts General Hospital: Rigotti Na et al, Clinical trial shows that cytisinicline can help people quit vaping, JAMA Internal Medicine (2024). DOI: 10.1001/jamainternmed.2024.1313

Thursday, January 2, 2025

Fingers of Science to Start 2025


Another year, another round of close-up photos of scientists holding small things in their rubber-gloved fingers. Nothing says science like a tiny piece of magic held by disembodied, rubber-gloved fingers, shoved right in front of the camera. Behold the fruits of human exploration:

Above image: Photostimulable polymer meta-surface - Jens Meyer University of Jena - Feb 2024

Airy cellulose from a 3D printer - Swiss Federal Laboratories for Materials Science and Technology - Apr 2024

Healable cathode material - David Baillot at UC San Diego Jacobs School of Engineering - Mar 2024

Precious metals extracted from discarded electronics - Fred Zwicky at University of Illinois Urbana-Champaign - Mar 2024

Synthetic mucus - Jessica Kramer for University of Utah - Mar 2024

2D semiconductor material by Xiangfeng Duan - UCLA Dehui Zhang - Apr 2024

A bag of extracted contaminants from an old pizza box - Idaho National Laboratory - Apr 2024

Prototype finger with rigid bones and flexible flesh - Adrian Alberola - Apr 2024

Zinc-lignin battery - Thor Balkhed Linköping University - May 2024

A bead of space glass, glass made in space - Phoenix Pleasant ORNL, USDOE - 2024

Smart bioelectronic bandage - Wei Gao California Institute of Technology - Jun 2024