Spray of tiny particles of gold can potentially treat heart disease, research suggests
Mar 2022, phys.org
Custom-made nanogold modified with peptides—a short chain of amino acids—was sprayed on the hearts of lab mice.
via University of Ottawa: Marcelo Muñoz et al, Nanoengineered Sprayable Therapy for Treating Myocardial Infarction, ACS Nano (2022). DOI: 10.1021/acsnano.1c08890
Lab grown, self-sustainable muscle cells repair injury and disease, mouse study shows
Apr 2022, phys.org
Scientists say they have successfully cultivated human muscle stem cells capable of renewing themselves and repairing muscle tissue damage in mice.
via Johns Hopkins University School of Medicine: Congshan Sun et al, Human pluripotent stem cell-derived myogenic progenitors undergo maturation to quiescent satellite cells upon engraftment, Cell Stem Cell (2022). DOI: 10.1016/j.stem.2022.03.004
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[Fucking transparent] Whole mouse chest after SARS-CoV-2 infection, Scripps Institute, 2022 [link] |
New method for making tissue transparent could speed the study of many diseases
Apr 2022, phys.org
A new tissue-clearing method for rendering large biological samples transparent.For studies of large body parts or even entire animals.Tissue-clearing methods until now have used either organic solvents or water-based solvents which require burdensome, labor-intensive procedures, often using hazardous chemicals. The new methods uses a sequential combination of organic solvents and water-based detergents, and makes use of water-based hydrogels to protect those molecules within the tissue that need to be preserved."In many cases, you can just put the whole thing in a jar and keep it in a shaker on your benchtop until it's done."
via Scripps Research Institute: Victoria Nudell et al, HYBRiD: hydrogel-reinforced DISCO for clearing mammalian bodies, Nature Methods (2022). DOI: 10.1038/s41592-022-01427-0
In Your Face, Gender Square:
Trichaptum mushrooms found to have more than 17,000 gender alleles
Apr 2022, phys.org
17,000
via University of Oslo and University of Michigan: David Peris et al, Large-scale fungal strain sequencing unravels the molecular diversity in mating loci maintained by long-term balancing selection, PLOS Genetics (2022). DOI: 10.1371/journal.pgen.1010097
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