Monday, December 8, 2025

Reproductive Sci Fi


AKA 3 People Babies:

Mitochondrial Donation in a Reproductive Care Pathway for mtDNA Disease, New England Journal of Medicine (the original article), July 2025 https://dx.doi.org/10.1056/NEJMoa2503658

"Pronuclear transfer" is the unsensational way to call this, but compare the headline above to the dominant media headlines:

  • Eight babies born after mitochondrial donation treatment to reduce transmission of mitochondrial DNA disease, Medicalxpress 
  • Healthy babies born in Britain after scientists used DNA from three people to avoid genetic disease, AP News 
  • Three-person IVF technique spared children from inherited diseases, scientists say, Reuters 
  • Babies from three people's DNA prevents hereditary disease, BBC
  • 8 babies born with DNA from 3 people in world-first IVF trial aimed at minimizing risk of inherited disease, CBS 
  • Babies born with DNA from three people hailed as breakthrough – but questions remain, The Conversation 
  • Eight healthy babies born after IVF using DNA from three people, The Guardian
  • Mitochondrial Donation and PGT to Reduce Risk of Mitochondrial DNA Disease, Newcastle University via New England Journal of Medicine 


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